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For a detailed month-by-month breakdown of what to expect during treatment, including when weight loss accelerates and when it typically plateaus, see our retatrutide weight loss timeline guide

GLP-1s are naturally-occurring hormones in the human body released from the gut after eating, and according to Mayo Clinic, GLP-1 medications are used to boost the amount of insulin our bodies make to keep our blood sugar within a normal range, as well as provide the sensation of fullness after a meal to curb cravings

Watanabe, PharmD, PhD, a professor of clinical pharmacy at the University of California San Francisco School of Pharmacy

However, whether or not albuminuria is a clinically relevant renal outcome remains unclear

GLP-1Rs are also expressed in platelets