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We sincerely thank all participants and their caregivers for their meaningful contributions. The class of drugs, derived from the protein in the venom of the Gila monster, a large black lizard with pink-orange markings, has sparked a revolution in the treatment of metabolic disease

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An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases