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Mutation of this enzyme leads to fumarate accumulation not only in skin cancer and uterine leiomyomas but also in breast, bladder, and Leydig cell tumors 130
Some people begin to notice mild headaches or water retention at this level
But they tend to be mild and manageable and go away the longer you take the medication
6 If gastric contents are present, deep sedation for either gastroscopy or colonoscopy should be reconsidered
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