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Glucagon like peptide-1 (GLP-1) is the natural ligand of GLP-1R
Diabetes 69(5):882892 Capozzi ME, Svendsen B, Encisco SE, Lewandowski SL, Martin MD, Lin H, et al (2019a) Cell tone is defined by proglucagon peptides through cAMP signaling
Drip some short-chain fatty acids onto L cells, and they start churning out PYY and GLP-1
This explains why energy metabolism is influenced by overall nutritional status, not just one single compound
Communicate regularly: Keep your healthcare provider updated on your routine and any side effects you notice
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