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When reading claims about maximizing endogenous release, check whether the cited study used physiologic meals or pharmacologic probes

For example, the North American Thrombosis Forum found that patients with inflammatory bowel disease (IBD) may have a 3-4 times higher risk of developing thrombosis (blood clots) than people without IBD. It is well-documented that Ozempic can cause significant gastrointestinal side effects, from diarrhea to gastroparesis

In vivo metabolic phenotyping: Assessment of body weight, food intake, and adiposity parameters in diet-induced obesity (DIO) rodent models following defined dosing schedules