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The field of pharmacogenomics using genetic information to target medicines could allow doctors to deliver treatments more likely to work and avoid those that could have harmful effects
We propose that curcumin exerts its broad therapeutic effects via a unified inflammationoxidative stress axis, primarily by inhibiting NF-B and NLRP3 activation, reducing ROS and pro-inflammatory cytokines (TNF-, IL-1/18), as seen across models of depression, metabolic disorders, and neurodegeneration
doi: 10.1007/s42000-024-00595-2 95
Cancer Causes Control 23 (3), 463471
Constant, non-pulsatile GH rise (as occurs with synthetic GH use) can lead to receptor desensitization, where target tissues become less responsive to growth hormone over time
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