A meta-analysis revealed that a 2.4 mg dose of semaglutide led to a reduction of 12.4 kg of body weight, while doses of 3.0 mg of liraglutide, 1.0 mg of semaglutide, and 1.8 mg of liraglutide led to reductions in body weight of 5.2 kg, 3.7 kg, and 1.8 kg, respectively
However, it is noteworthy that resmetirom showed an improvement in certain liver pathology measurements in only 2530% of patients
It can improve blood sugar, blood pressure, cholesterol levels, and inflammatory markers, supporting long-term health improvements
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SELECT showed direct cardiovascular benefit of semaglutide in patients with established cardiovascular disease and overweight or obesity