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The Phase 3 ENLIGHTEN-Fibrosis trial in non-cirrhotic (F2-F3) MASH and Phase 3 ENLIGHTEN-Cirrhos is trial in compensated cirrhotic (F4) MASH continue to enroll patients, with topline data from the histology cohorts of these trials expected in the first half of 2027 and in 2028, respectively

5-Amino-1MQ works by inhibiting NNMT (nicotinamide N-methyltransferase), an enzyme that depletes cellular NAD+ and SAM

And 4 out of 5 people find symptom relief with a course of Accutane

Tirzepatide also improves liver fat, primarily through weight loss and improved insulin sensitivity

from May 2023, they are an employee and shareholder of Eli Lilly