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The HCO 3 produced by the proximal tubule via glutamine metabolism represents new HCO 3 being added to the pool already in the blood, thereby enhancing the buffering capacity of the blood

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Finally, compared with full-term infants, preterm infants had 2.5 higher sulfur AAs levels and 1.7 higher levels of taurine, a cysteine-degradation product, in venous cord blood, with the highest levels in NAC-treated moderate IPTB cases (see details in legend Supplementary Table S5)