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Although previous ex vivo studies employing NCI-H716 cells (a human L cell line) [35] or human ileal and colonic tissues [14] were indicative of a direct effect of metformin in stimulating GLP-1 release, clinical evidence suggests that the augmentation of postprandial GLP-1 secretion by metformin is largely indirect
These conditions often develop silently
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Effects of liraglutide on depressive behavior in a mouse depression model and cognition in the probe trial of Morris water maze test
2,3 Concurrently, type 2 diabetes (T2D) is a significant global health problem
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