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4 Oxidative stress plays a central initiating role in the pathogenesis of vitiligo: the high metabolic activity of melanocytes leads to excessive generation of reactive oxygen species (ROS), while functional defects in the skins antioxidant system result in ROS accumulation, directly triggering mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis

However, if you already have an overabundance of bacteria in the wrong places (like your small intestine), prebiotics will exacerbate your symptoms

Vitamin B12 Deficiency Anemia FAQs Why are vegetarians more prone to vitamin B12 deficiency

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Comparison of early corneal endothelial cell loss after coaxial phacoemulsification through 1.8 mm microincision and bimanual phacoemulsification through 1.7 mm microincision