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Careful patient selection is essential to avoid inappropriate expectations or complications
[9] [2] According to NICE guidance, patients with confirmed B12 deficiency and neurological involvement typically require more frequent initial dosing (alternate-day injections) until symptom improvement occurs
It targets and inhibits the activity of an enzyme known as NNMT, which has been linked to a slowdown in metabolism and a reduction in energy production
Gastrointestinal absorption of vitamin B 12 depends on the presence of sufficient intrinsic factor and calcium ions
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