Although short-term trials show minimal adverse effects, the prolonged intake of agents such as selenium, vitamin D, and zinc can lead to toxicity if not monitored adequately 58
Animal data on food conversion efficiency suggests calories are partitioned more aggressively toward lean tissue (Tomas et al., 1993), but appetite responses are variable
The global, regional and national burden of type 2 diabetes mellitus in the past, present and future: a systematic analysis of the Global Burden of Disease Study 2019
This may include: Assessment for fecal impaction (digital rectal exam or imaging) Evaluation for other causes of constipation (hypothyroidism, medication interactions, structural issues) Discussion of dose reduction or treatment alternatives Prescription motility agents (prucalopride, linaclotide) Referral to gastroenterology for refractory cases Foods and supplements that worsen GLP-1 constipation Constipating foods to limit or avoid: Processed foods low in fiber
That combination deserves a real clinical conversation, not a thread on a forum