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Its 15-amino-acid sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) has shown cytoprotective and regenerative activity across multiple organ systems in preclinical research [1]
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Under the influence of GH, IGF-1 and IGFBP-3 can stimulate the proliferation of epiphyseal plate, promote the synthesis of collagen and sulfated mucopolysaccharide, participate in the regulation of protein metabolism, and hence promote growth and improve height [29]
Another study reported that 28-day oral exposure to polystyrene (PS) microplastics resulted in a reduction in the number of Nissl bodies and affected the cellular architecture of neurons (13)
The behavioral tests included the self-grooming test that served as a measure of repetitive behavior
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