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However, if someone already has extremely high levels of vitamin B (from taking excessive supplements and showing toxicity symptoms), further pyridoxine would be avoided

Many individuals cycle through active treatment and maintenance phases over extended periods

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Pernicious Anemia: If treating pernicious anemia, you may have to use Vitamin B12 Injections for the rest of your life

You can also learn more about vitamin B12, weight loss, and wellness by exploring the ThinWorks blog and client resources. Final Takeaway: The Best Time to Take Vitamin B12 For most people, the best time to take vitamin B12 is in the morning or early afternoon, ideally on an empty stomach with a glass of water, so it can support daytime energy and avoid potential sleep disruption