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Importantly, these insulin sensitizing effects are dependent on functional TRPV1 signaling, as capsaicin fails to improve diet-induced insulin resistance in TRPV1-deficient mice (52)
Bupropion is a norepinephrine-dopamine reuptake inhibitor that increases alertness and reduces appetite by elevating dopamine and norepinephrine in the brain's appetite-control centers
MICC (Methionine, Inositol, Choline, Cyanocobalamin) MICC is a compounded blend of four nutrients: methionine, inositol, choline and cyanocobalamin (a form of vitamin B12)
Early evidence suggests that individuals using GLP-1s spend significantly less money at the grocery store, shifting their purchasing habits away from snacks, alcohol, and carbohydrates while also increasing demand for high-protein and nutrient-dense foods (e.g., Roe, 2025
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The most common adverse events were gastrointestinal in nature, consistent with incretin-based therapies, and were generally mild to moderate in severity
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