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Potential drug interactions have not been systematically studied

Some studies suggest the quinolinium structure is sufficiently NNMT-selective that it should not broadly deplete SAM, but the wider metabolic picture remains an active research consideration

Do not freeze the vial, and do not use the solution if it looks cloudy, discolored, or contains visible particles

Water retention or mild bloating: Small amounts of fluid retention can occur when starting peptide analogues of growth hormone because growth hormone causes sodium and water retention in the tissues, resulting in slight puffiness or bloating