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DNA methylation dynamics of genomic imprinting in mouse development
In addition, at 5 years, significantly fewer GLP-1 drug users (13.5%) than nonusers (19.9%) had died, for a 31% lower mortality risk with GLP-1 drug use (aSHR = 0.69
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Whether all of these data can be extrapolated to clinical practice remains a matter of debate
If tirzepatide remains ineffective despite optimization of all modifiable factors, alternative GLP-1 receptor agonists or other weight management medications may be considered
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