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Increased Energy and Stamina B-vitamins help convert carbohydrates, fats, and proteins into usable energy, reducing fatigue and improving endurance

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Methionine, in the form of S-adenosylmethionine (SAM), is required for many methylation reactions, including DNA methylation

57 Positive effects of B12 on homocysteine levels have also been observed in other patient populations, including healthy adults, 46 vegetarian women, 58 generally healthy women, 59 older adults with elevated MMA and homocysteine, 37 and patients with type 2 diabetes mellitus

This deficiency can result from conditions such as pernicious anemia, certain gastrointestinal disorders, or a diet low in animal products