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In addition to life-sustaining nutrient absorption and excretion, our intestines wield many responsibilities--chief amongst them include regulating pancreatic and stomach secretions, metabolism, nervous system function and behavior ( Figure 1 )

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The model was first fitted to the training concentrations (37.5 and 25 M doxorubicin), and then used to simulate the test concentrations (50, 12.5 and 10 M doxorubicin) as a means of blind validation, showing good accordance between the experimental and in silico outputs for all concentrations of doxorubicin

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