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4 Mechanisms of hepatoprotection by GLP-1RAs as immune-metabolic modulators 4.1 Immunomodulatory mechanism of hepatic injuries by GLP-1RAs GLP-1RAs reduce inflammation, downregulate pro-inflammatory cytokines, and influence immune cell differentiation via the GLP-1 receptor, which alters macrophage polarization and inhibits fibrosis (Hammerich and Tacke, 2023)
If you experience persistent nausea or other concerning symptoms, adjusting your dose level or pausing dose escalation is more appropriate than attempting to change the dosing schedule
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