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This ongoing oxidative stress leaves endothelial cells (the lining of blood vessels) highly vulnerable to ongoing damage, contributing to the micro-clotting and "immunothrombosis" frequently observed in Long Haulers

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

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In brief, the mice were administered a daily topical application of 62.5 mg of 5% imiquimod cream (Mingxinlidi, Sichuan, China) on their shaved backs for seven consecutive days

Pollard & Pomfrett suggest that DSIP administration doesnt induce tolerance,4 but theirs isnt the consensus conclusion