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During disease progression, the accumulation of aberrant proteins can overwhelm the cellular chaperone system, as the demand for refolding and clearance exceeds its capacity 97

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In people with chronic diseases, glutathione may be discussed as part of the underlying biology of the condition rather than as a separate diagnosis

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After 30 min of ischaemia, mice were sacrificed by cervical dislocation with the occlusion suture left in situ to prevent reperfusion

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