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Malabsorption issues (e.g., digestive disorders like Crohns or celiac disease)
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Nat Rev Endocrinol (2014) 10:293302
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Given that the effectiveness of NAC for treating APAP-induced liver injury is confined to modest improvements within a brief period after onset and considering that high doses of NAC can potentially negatively impact hepatocyte metabolism and liver regeneration (Jaeschke et al
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