However, Mathiesen et al
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Its sequence AcNlecyclo[AspHisDPheArgTrpLys]NH incorporates a norleucine substitution, a Dphenylalanine substitution, and a lactam bridge that cyclises the molecule, conferring markedly greater stability and resistance to enzymatic degradation than the native linear hormone
Likewise, BPC 157 helped re-establish full tendon integrity
Disruptions to this equilibrium can lead to oxidative stress, mitochondrial dysfunction, and aberrant energy metabolism [150]