People react differently to medication for a variety of reasons
Incretins are largely degraded by DPP-4 in vivo, which can be hindered by substitution of first three residues or increasing steric hindrance
However, there is potential for more serious adverse effects, such as: 1 Vision problems Swelling in the extremities Dizziness or fainting Reduced urination Rash Rapid heart rate Swelling of the throat, tongue, mouth, face, or eyes Problems swallowing or breathing Fever Yellow eyes or skin Chronic upper stomach pain Wegovy, another brand name for semaglutide, may also cause damage to the retina, suicidal ideation, gallstones, pancreatitis, and acute kidney damage
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Keep a symptom diary noting any side effects, changes in appetite, and blood glucose readings if applicable