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Hydroxocobalamin is preferred because it binds more tightly to serum proteins, creating a depot effect that allows slower release and longer duration of action

It is an essential nutrient which is water soluble

The critical concept here is bioavailability which is just a fancy word for how much of a nutrient your body can actually absorb and put to work

Neurological Manifestation Treatment Doses For those with B12 deficiency symptoms like nerve problems or brain fog, treatment needs to be stronger