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Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist, a class of medication that mimics a hormone your body naturally produces to regulate appetite and blood sugar

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and changes from baseline in BMI, waist circumference, blood pressure, and fasting lipids

Across clinical trials, these medications typically lower systolic blood pressure by a modest but clinically meaningful amount, ~3-6 mmHg on average, alongside reductions in antihypertensive medication use, said Jordana Cohen, MD, a volunteer expert at the American Heart Association and associate professor of medicine and epidemiology at the Perelman School of Medicine at the University of Pennsylvania