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In phase III trials in patients with type 2 diabetes, once-weekly subcutaneous administration of semaglutide has been shown to significantly improve glycaemic control and reduce body weight compared with placebo when given as monotherapy, and compared with sitagliptin, extended-release exenatide or insulin glargine when given as add-on therapy to oral antidiabetic drugs [5,6,7,8]
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47 The 2026 China Patent Cliff: A Global Inflection Point China, the second-largest pharmaceutical market in the world, is facing an imminent patent cliff for semaglutide
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doi: 10.3389/fphar.2021.681338 87 TangXDingHLiangMChenXYanYWanNet al
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