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10.1007/s00374-013-0894-3 Biol

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Conversely, dietary patterns such as the Mediterranean diet, rich in antioxidants, polyunsaturated fatty acids, and anti-inflammatory components, have demonstrated protective effects against cognitive decline and neurodegeneration, potentially by preserving gut microbiota balance and reducing systemic and neuroinflammation

This makes bedtime dosing optimal, as it amplifies the natural nocturnal GH surge without disrupting the diurnal secretory rhythm