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Description

Semaglutide, a GLP-1 receptor agonist, reaches steady-state blood levels after four to five weeks of once-weekly dosing, with a half-life of approximately one week

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12 , e1001871 (2014)

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PMID: 25165638

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Synthetic GLP-1 receptor agonists are long acting with a 13 hour half-life and have been shown to improve glycemic control and aid in weight loss

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8, 2023, the FDA approved Zepbound (tirzepatide) injection, the first and only obesity treatment of its kind that activates both GIP and GLP-1 hormone receptors

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