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Most research protocols use 100 to 300 mcg per shot , one to three times per day

Oral glucose administration results in up to three times more insulin being released than direct -cell glucose sensing, highlighting the glucoregulatory impact of glucose-induced GLP-1 and GIP release from EECs 118,119

Many studies had small sample sizes or no long-term follow-up

Patients with pre-existing mental health conditions, including anxiety disorders, should not be automatically excluded from GLP-1 treatment, but may benefit from closer monitoring and coordinated care between their GP, diabetes specialist, and mental health professionals

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