Given the lack of liver GLP-1R expression (136), the potential mechanism of actions of GLP-1R agonists in NASH may be related to the indirect beneficial effects on body weight, IR and reduction in metabolic dysfunction, lipotoxic effects and inflammation (49, 137)
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Theranostics 11 (7), 30523059
These include changes in the size and pigmentation of moles, rapid appearance of new moles, flushing to the face, abdominal cramps, nausea, vomiting, chest pain and brain swelling
So, its important to follow your prescribers guidance and never adjust doses on your own