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Most retatrutide-related diarrhea is mild to moderate, peaks during dose escalation, and resolves within 8 to 12 weeks for the majority of participants

Telehealth consultations may be available when clinically appropriate

2.4 Statistical analysis The AE reports were analyzed for signal detection using two-by-two contingency tables (Table 1) and four algorithms: the ROR, the PRR, the BCPNN, and the EBGM (shown in Supplementary Table S2)

Importantly, GLP-1 therapies have not been associated with an increased risk of pancreatitis or thyroid cancer in clinical trials

But it may be related to how Wegovy works for weight loss