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the FDA has stated it lacks sufficient information to know whether the substance would cause harm when administered to humans Evidence snapshot: The evidence base is almost entirely preclinical, decades of animal (largely rat) studies, mostly from one Croatian research group (Sikiric et al., University of Zagreb), with a single small human trial under the brand name "Bepecin" (around 2015) that did not lead to any FDA-approved use
After one year: People who switched from Wegovy to orforglipron maintained almost all their weight loss, with an average regain of about 2 lb
For further guidance, please refer to our peptide reconstitution page
10.3389/fnmol.2024.1388759 92 GuoM.CaoQ.XiaS.CaoX.ChenJ.QianY.et al (2023)
