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If someone is unwilling to track their progress or adjust based on how their body responds, the medication will be less effective
doi: 10.1038/jcbfm.2009.73 13
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Researchers randomly assigned 751 adults with obesity (but without type 2 diabetes) to receive either tirzepatide or semaglutide once a week by injection for 72 weeks that's about 17 months
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