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the guide is the canonical reference
Irritable Bowel Syndrome (IBS) and leaky Gut Syndrome Improvement of intestinal barrier function BPC 157 can up-regulate the expression of tight junction proteins (such as Occludin and ZO-1), enhance the integrity of the intestinal barrier, and reduce bacterial and toxin translocation
There are trade-offs, of course
As in the previous recommendations by the ADA and EASD (73, 74), life-style intervention (with patient education and motivation, increase of physical activity, and healthy eating) is still in the beginning and center of therapy, followed by pharmacological therapy with metformin (7074)
This concern comes up regularly, and it is worth addressing directly
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