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Availability of data and materials Data supporting the findings of this study are available from the corresponding author upon reasonable request by a qualified researcher and upon approval by the data-clearing committee of the Medical University Vienna

Metformin remains the first-line therapy for newly diagnosed pediatric patients

Cell reagents Cells and organoids were treated with the following compounds as indicated: 5FU (Abcam, ab142387-5g

Between 2019 and 2023, the number of GLP-1 prescriptions increased by more than 400%, while spending increased by more than 500%

Pharmacogenetics in clinical pharmacology and toxicology