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I understand how these might slow the rate of progression in a general sense using multiple mechanisms. For example, diabetes, cardiovascular disease, and obesity are all risk factors for developing dementia, so using GLP-1 agonists to improve these various aspects of health may, in turn, protect cognition

However, retatrutide does cause some effects not typically seen with Wegovy, including a small increase in heart rate and skin sensitivity

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PD-1 agonist treatment improved airway hyperresponsiveness (AHR) in allergic asthma and suppressed lung inflammation in a humanized mouse model by controlling lung ILC2 transcriptional profiles and cytokine production and limiting type 2 innate lymphocyte (ILC2) proliferation through metabolic regulation and reducing ILC2-mediated Th2 cytokine secretion (97)