Biggest breakthrough since statins GLP-1s are classed as receptor agonists, or drugs that activate at specific receptors in the body
Additionally, a study published in The Lancet in February 2026 found that taking Foundayo, Eli Lillys GLP-1 pill that was approved by the FDA in April, resulted in greater weight loss and blood sugar level reductions compared to Rybelsus, another oral GLP-1 manufactured by Novo Nordisk
In the only published human study, to our knowledge, looking at appetitive and metabolic hormones, smoked medicinal cannabis (as a treatment for neuropathic pain) was tested in adult men positive for human immunodeficiency virus (HIV)
Oxytocin, on the other hand, is believed to enhance sexual pleasure and satisfaction, potentially improving overall sexual performance
Some people who cannot tolerate semaglutide do well with tirzepatide, and vice versa