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These sugars cause rapid spikes in blood glucose levels, which can result in energy surges followed by crashes

Blankenberg, S., Rupprecht, H

Deane AM, Nguyen NQ, Stevens JE et al (2010) Endogenous glucagon-like peptide-1 slows gastric emptying in healthy subjects, attenuating postprandial glycemia

Tirzepatide (Mounjaro/Zepbound) activates GLP-1 and GIP receptors

Additionally, some individuals may experience an increased risk of hypoglycemia (low blood sugar) when taking semaglutide, particularly if they are also using insulin or other diabetes medications