Constipation, while less common than diarrhea, may also occur and can be particularly problematic in patients with pre-existing constipation issues
During a caloric deficit, when your body might otherwise break down muscle for energy, the increased IGF-1 levels help signal your body to preserve muscle tissue while preferentially burning fat
If this happens, switch to cold hard-boiled eggs (smell less than hot), egg whites only, or skip eggs temporarily and use other protein sources like Greek yogurt, cottage cheese, or protein shakes until nausea resolves
Personal Opinion: The energy improvements I have observed in menopausal women using Retatrutide often exceed what weight loss alone would explain
Secher A, Jelsing J, Baquero AF, Hecksher-Sorensen J, Cowley MA, Dalboge LS, Hansen G, Grove KL, Pyke C, Raun K, Schaffer L, Tang-Christensen M, Verma S, Witgen BM, Vrang N, and Bjerre Knudsen L