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Retinal Disorders in Patients with Type 2 Diabetes In a trial of adult patients with type 2 diabetes and BMI greater than or equal to 27 kg/m 2 for weight reduction, retinal disorders were reported by 6.9% of patients treated with WEGOVY (semaglutide 2.4 mg), 6.2% of patients treated with semaglutide 1 mg, and 4.2% of patients treated with placebo
However, under H 2 O 2 -treated conditions, nuclear MOTS-c increased to a greater extent than mitochondrial MOTS-c, suggesting a mitochondrial-to-nuclear translocation of MOTS-c (Fig
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