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Caution in patients with gastrointestinal motility disorders, renal impairment, or history of pancreatitis

Accessed on May 14, 2025 at Cutlet, R., et

Not clinically dangerous, but over weeks and months of injections, consistent overdosing or underdosing compounds

The sustained activation characteristic of Retatrutide's extended half-life could potentially disrupt normal nerve function through prolonged metabolic alterations or inflammatory pathway activation

For individuals with Type 2 diabetes, who are at an increased risk for heart disease, GLP-1 therapy has been shown to lower the risk of heart attack, stroke, and other cardiovascular events