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Pregnancy, breastfeeding, and planned surgery should also be discussed before use

Similarly, older in vitro studies utilizing basophilic leukemia cell lines (RBL-2H3) demonstrated that pre-incubation with just 10 M of lycopene cut the release of -hexosaminidase (the primary marker of mast cell degranulation) in half

Mucosal administration pathways covering nasal, oral and buccal routes possess prominent merits, including convenient operation, pain-free injection and favorable initial patient compliance, which endow them with bright prospects for chronic disease treatment

Additionally, the pressure from a full stomach can force stomach acid upward, causing severe heartburn or acid reflux

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