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As shown in Table 4, there was highly significant increase in the of frequency of defecation in KD with L-carnitine supplementation group by 50% in comparison to KD only group that showed decrease in frequency of defecation per week by 33%

Sigma-Aldrich, Madrid, Spain) and cultured in RPMI 1640 medium supplemented with 10% heat-inactivated FBS, penicillin, streptomycin, L-glutamine, and 50 U/mL of human recombinant interleukin 2 (IL2) [49]

& Benahmed, M

134 These observations underscore the complex and context-dependent effects of ERAD in adipose tissue, linking local proteostasis to systemic lipid homeostasis