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The collapse of both astrocyte and microglia into pro-inflammatory states due to depletion of GSH, leading to sustained neuroinflammation and oxidative stress, is observed in many neurodegenerative diseases (Ferreira et al., 2013
doi: 10.1177/002215540205000208, 35
In particular, functions of all GST members including Lambda class GSTs need to be explored because of its importance in As stress response
Translational animal models for Alzheimer's disease: an Alzheimer's association business consortium think tank
A decision is expected in Q4 2026 approximately October to December
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