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These events were generally mild to moderate , occurred predominantly during dose escalation, and often decreased in frequency or intensity as participants adapted to the target dose
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While the patient groups did not differ by sex, M/M were of slightly lower age relative to both HC and SA and, unsurprisingly, higher fractional exhaled nitric oxide (FeNO) and lower FEV 1 (% predicted) were observed across groups from HC to SA
It can worsen GI side effects, particularly nausea and bloating
The consequences of glutathione deficiency are related to increased oxidative stress and can manifest either as immune system disorders (disease) or enzyme malfunction ultimately promoting damage to cellular structures, an accelerated aging process, and aggravation of existing diseases
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