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STOP-NIDDM Trail Research Group

Hypothesis 4 Body composition Retatrutide's glucagon-receptor activation drives some of its weight loss through increased energy expenditure, which is mechanistically associated with sparing more lean mass than pure-satiety pathways

Diabetes Ther 12(1):143157

Some protocols discuss administering injections near the area of concern, but patients should follow the route and injection location provided by their prescribing clinician

A limitation of this study is that the 1 H-fMRS sequence did not include interleaved unsuppressed water acquisitions, which are necessary for reliable water-scaled metabolite quantification adjusted for tissue type or relaxation differences