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The growing interest in GLP-1 stems partly from the success of GLP-1 receptor agonist medications (such as semaglutide and liraglutide) in treating type 2 diabetes and obesity
Entre los mecanismos operativos, se postulan efectos protectores de SEMA sobre el remodelado cardiaco con disminucin de la hipertrofia y la fibrosis con mejora de la funcin mitocondrial, de la funcin microvascular y la reduccin de apoptosis demostrados tanto en modelo experimental como clnico27,28, as como otros efectos metablicos relacionados con la reduccin de masa grasa (fig
J Biol Chem 277 : 3079230797
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